Search on: RECEPTORS, TOLL-LIKE 
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Descriptor English:   Toll-Like Receptors 
Descriptor Spanish:   Receptores Toll-Like 
Descriptor Portuguese:   Receptores Toll-Like 
Synonyms English:   Receptor, Toll-Like
Receptors, Toll Like
Receptors, Toll-Like
Toll Like Receptor
Toll Like Receptors
Toll-Like Receptor  
Tree Number:   D12.776.543.750.705.910.500
Definition English:   A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS. 
Indexing Annotation English:   general; prefer specifics
History Note English:   2006(1998) 
Allowable Qualifiers English:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   51130 
Unique Identifier:   D051193 

Occurrence in VHL:
 

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